Nuno Espirito Santo has never been someone who makes changes to his team for the sake of it, and that is expected to be the case this weekend.

After Tottenham Hotspur defeated Newcastle United by a 3-2 scoreline last Sunday, the Portuguese opted to rest each of the players who started at St James' Park for the European fixture in midweek.

The players who were involved against Vitesse had an opportunity to stake their claim for a second start in quick succession ahead of Spurs' Premier League fixture at West Ham United.

However, Nuno watched on helplessly as his side succumbed to a 1-0 defeat in the Netherlands, a result which effectively makes his next selection a foregone conclusion.

Tanguy Ndombele will remain ahead of Dele Alli in the pecking order, particularly after getting on the scoresheet against the Magpies.

Lucas Moura will continue to feature ahead of Steven Bergwijn on the right flank, while Harry Winks has been left still searching for a way back into the team ahead of Oliver Skipp.

Even though two goals were conceded in the North-East, Sergio Romero and Eric Dier will almost certainly retain their places in the middle of the defence.

There has been much criticism of Harry Kane's contribution this season, but the forward heads into this fixture with five goals and an assist from his last four outings in all competitions.

Tottenham Hotspur possible starting lineup: Lloris; Emerson, Romero, Dier, Reguilon; Skipp, Hojbjerg; Moura, Ndombele, Son; Kane